sulfasalazine side effects

"Product Information. Fatigue/drowsiness is less common, but is still a known side effect. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Several potentially dangerous side effects have been reported rarely with sulfasalazine. Can Med Assoc J 131 (1984): 43-5, 13. All symptoms resolved within 2 months after discontinuing sulfasalazine. Also nausea for the initial 4 weeks. Losek JD, Werlin SL "Sulfasalazine hepatotoxicity." Keisu M, Ekman E "Sulfasalazine associated agranulocytosis in sweden 1972-1989: clinical features, and estimation of its incidence." This is the best approach IMO. Hello there, I can't answer your question specifically but I am just starting my third week on Sulfa. Common side effects of Azulfidine include gastrointestinal disturbances, headache, allergic reactions, rash when exposed to sunlight, and changes in skin or urine color. I woke up this morning feeling like I had an awful hangover, headache and nausea. Pharmacotherapy 15 (1995): 176-81, 45. Available for Android and iOS devices. Skeith KJ, Russell AS "Adverse reaction to sulfasalazine." Side effects… Pena JM, Gonzalez-Garcia JJ, Garcia-Alegria J, Barbado FJ, Vazquez JJ "Thrombocytopenia and sulfasalazine." Clin Nephrol 71 (2009): 74-9, 59. Temperature 3. headache (continuing) 4. increased susceptibility of skin to sun 5. skin rash or itching 6. vomiting 7. Sulfasalazine just didn't work at all for me unfortunately so I'm now on a combination of Sulfasalazine … Sulfasalazine can have a number of side-effects, many of which are minor. Feel Like Throwing Up 5. Veteran Member. Hepatitis has been reported in patients with sulfasalazine hypersensitivity. Can interfere with lab test results, so let your doctor know if you're taking this drug. A drop in white blood cell count or a type of anemia in which red blood cells are disrupted (hemolyzed) may occur. You may report side effects to FDA at 1-800-FDA-1088. J Pediatr Gastroenterol Nutr 9 (1989): 261-3, 37. Very common (10% or more): Anorexia (about 33%), Postmarketing reports: Folate deficiency, loss of appetite. Am J Gastroenterol 89 (1994): 789-91, 17. You may be able to increase the dose again after a while if your reaction to sulfasalazine improves and it’s helping your symptoms. The most common adverse reactions associated with Sulfasalazine are anorexia, headache, nausea, vomiting, gastric distress, and apparently reversible oligospermia. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. The most common side effects reported were anorexia, headache, nausea, vomiting, gastric distress, elevated temperature, erythema, pruritus, rash, loss of appetite, and reversible oligospermia. Patients most commonly developed arthralgias and pleuritic chest pain. Common side effects of Azulfidine include gastrointestinal disturbances (nausea, vomiting, gastric distress, and loss of appetite), headache, allergic reactions, and photosensitivity (development of a rash when exposed to sunlight), … Sulfasalazine has many more side effects than the mesalamines do. Schwartz AG, Targan SR, Saxon A, Weinstein WM "Sulfasalazine-induced exacerbation of ulcerative colitis." Mayo Clin Proc 59 (1984): 343-6, 67. Azulfidine (sulfasalazine)." Nausea/vomiting 4. The most common side effects include: Upset stomach; Diarrhea; Nausea/vomiting; Headache; Appetite loss; Skin sensitivity; Approximately 10% of patients taking Sulfasalazine experience a skin rash. When taking Sulfasalazine, reported side effects are usually mild and improve in time. Nielsen OH "Sulfasalazine intolerance. Boxermom was prescribed sulfazine to address her joint pain. Nausea is VERY common with sulfasalazine (as in. Rash 5. Gabazza EC, Taguchi O, Yamakami T, Machishi M, Ibata H, Suzuki S, Matsumoto K, Kitagawa T, Yamamoto J "Pulmonary infiltrates and skin pigmentation associated with sulfasalazine." effective and no serious side effects occur. N Engl J Med 306 (1982): 409-12, 15. Hill ME, Gordon C, Situnayake RD, Heath DA "Sulfasalazine induced seizures and dysphasia." Patients often presented with fever and sore throat. Bone marrow hypoplasia or aplasia was usually confined to the myeloid series, but may be accompanied by erythroid hypoplasia and marrow plasmacytosis. Some of the most common sulfasalazine side effects include headache, low sperm count in men, and nausea. Wang KK, Bowyer BA, Fleming CR, Schroeder KW "Pulmonary infiltrates and eosinophilia associated with sulfasalazine." Sulfasalazine may react with many different medicines in … [Ref], Common (1% to 10%): Abnormal liver function tests, Uncommon (0.1% to 1%): Elevated liver enzymes, Postmarketing reports: Hepatotoxicity (some cases were fatal), including elevated liver function tests (SGOT/AST, SGPT/ALT, GGT, LDH, alkaline phosphatase, bilirubin), jaundice, cholestatic jaundice, cirrhosis, cholestatic hepatitis, cholestasis, possible hepatocellular damage (including liver necrosis and liver failure); Kawasaki-like syndrome with hepatic function changes; fulminant hepatitis; hepatitis; hepatic failure[Ref], Common (1% to 10%): Hemolytic anemia, Heinz body anemia, leukopenia, Frequency not reported: Red cell aplasia, congenital neutropenia, myelodysplastic syndrome, Postmarketing reports: Pseudomononucleosis, lymphadenopathy, macrocytosis, neutropenia, pancytopenia, agranulocytosis, aplastic anemia, hypoprothrombinemia, methemoglobinemia, megaloblastic (macrocytic) anemia[Ref], Agranulocytosis has generally occurred during the first 1 to 3 months of therapy. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Veteran Member. The most common adverse reactions associated with sulfasalazine are anorexia, headache, nausea, vomiting, gastric distress, and apparently reversible oligospermia.These occur in about one-third of the patients. A few also presented with a rash. Copyright © 2020 IBM Watson Health. Sulfasalazine is known as a disease modifying anti-rheumatic drug (DMARD).. Aust N Z J Med 22 (1992): 391-2, 54. Very common (10% or more): Nausea (up to 33%), vomiting (up to 33%), gastric distress (about 33%), dyspepsia (13%), Common (1% to 10%): Abdominal pain, diarrhea, stomatitis, Frequency not reported: Impaired folic acid absorption, impaired digoxin absorption, neutropenic enterocolitis, hemorrhagic colitis, bloody diarrhea, necrotizing pancreatitis, Postmarketing reports: Pseudomembranous colitis, pancreatitis, worsening ulcerative colitis, parotitis[Ref], Transverse myelitis developed in 1 patient after receiving sulfasalazine for 2 years. J Pediatr 92 (1978): 450-1, 2. I have been struggling with a lot of relatively small issues some of which may be more to do with build up of toxicity due to mtx perhaps - I find it hard to tell which drug is doing what & then to differentiate side effects from random RA symptoms. Like all DMARDs, sulfasalazine takes time to work. Diarrhea 3. Fertility returns when the medicine is stopped. Sulfasalazine is very well tolerated, with 80% of patients experiencing no side effects. These side effects usually happen during the first three months of treatment and often clear up if the dose is lowered. Sulfasalazine may make you … Dig Dis Sci 28:833–842, 1983. Less frequent adverse reactions are skin rash, pruritus, urticaria, fever, Heinz body anemia, hemolytic anemia, and cyanosis, which may occur at a frequency of one in every thirty patients or less. Although not all of these side effects may occur, if they do occur they may need medical attention. Significant side effects occur in about 25% of people. "Drugs for rheumatoid arthritis." Angioedema was reported during postmarketing experience with the use of products containing or metabolized to mesalamine. What are the side effects? I am on my 4th week of taking Sulfasalazine (at full does of 2 in the morning and 2 in the evening since Sunday). Dig Dis Sci 28 (1983): 833-42. Eur J Clin Pharmacol 43 (1992): 215-8, 52. Br Med J 320 (2000): 1113, 48. Leroux JL, Ghezail M, Chertok P, Blotman F "Hypersensitivity reactions to sulfasalazine: skin rash, fever, hepatitis and activated lymphocytes." Dizzy 4. It is considered by some to be a first line treatment in rheumatoid arthritis. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. The risk of Stevens-Johnson syndrome or toxic epidermal necrolysis increased largely with the use of sulfonamides; however, these phenomena were rare as a whole. Sulfasalazine (brand names Pyralin EN, Salazopyrin EN) is a medicine - a combination of an aspirin-like anti-inflammatory component and a sulphur antibiotic-like component - used to treat rheumatoid arthritis. Call your doctor for medical advice about side effects. Guillemin F, Aussedat R, Guerci A, Lederlin P, Trechot P, Pourel J "Fatal agranulocytosis in sulfasalazine treated rheumatoid arthritis." If you notice any other effects, check with your healthcare professional. It also changes the color of the urine and tears making it slightly yellow-orange. Sulfasalazine is a prodrug, which is used in the treatment of ulcerative colitis, bowel inflammation, and diarrhea. Alloway JA, Mitchell SR "Sulfasalazine neurotoxicity: a report of aseptic meningitis and a review of the literature." Hello, I have been on sulfasalazine for 5 months and currently take 3000 mg a day and so far it worked well, I'm getting better slowly with no side effects. Scand J Gastroenterol 17 (1982): 389-93, 8. Am J Dis Child 135 (1981): 1070-2, 32. Chatzinoff M, Guarino JM, Corson SL, Batzer FR, Friedman LS "Sulfasalazine-induced abnormal sperm penetration assay reversed on changing to 5-aminosalicylic acid enemas." Aching of joints 2. [Ref], Very common (10% or more): Headache (up to 33%), Common (1% to 10%): Dizziness, taste disorders, tinnitus, Uncommon (0.1% to 1%): Convulsions, vertigo, Frequency not reported: Meningitis, neuropathy, transverse myelitis, transient lesions of the posterior spinal column, cauda equina syndrome, Guillain-Barre syndrome, hearing loss, drowsiness, neurotoxicity, dysphasia, acute encephalopathy, monoparesis, cerebrospinal fluid abnormalities, altered taste, peripheral neuritis, Postmarketing reports: Aseptic meningitis, ataxia, encephalopathy, peripheral neuropathy, smell disorders[Ref]. Symptoms typically resolved over several weeks to several months. Pokorney BH, Nichols TW, Jr "Pseudomembranous colitis. Dwarakanath AD, Michael J, Allan RN "Sulphasalazine-induced renal failure." 30. J Rheumatol 18 (1991): 634-5, 5. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. I’ve been on 500mg 2x daily for nearly 4 weeks now(had to switch to delayed release tab- stomach side effects were awful) and also take Actemra self injection weekly with 20 … Head Pain 6. The following side effects have been reported as hypersensitivity reactions: erythema multiforme (Stevens-Johnson syndrome), exfoliative dermatitis, epidermal necrolysis (Lyell's syndrome) with corneal damage, drug rash with eosinophilia and systemic symptoms (DRESS), anaphylaxis, serum sickness syndrome, pneumonitis (with or without eosinophilia), vasculitis, fibrosing alveolitis, pleuritis, pericarditis (with or without tamponade), allergic myocarditis, polyarteritis nodosa, lupus erythematosus-like syndrome, hepatitis and hepatic necrosis (with or without immune complexes), fulminant hepatitis (sometimes leading to liver transplantation), parapsoriasis varioliformis acuta (Mucha-Haberman syndrome), rhabdomyolysis, photosensitization, arthralgia, periorbital edema, conjunctival and scleral injection, alopecia, and interstitial lung disease. Frequency of side effects increased with daily doses of 4 g or more, or total serum sulfapyridine levels above 50 mcg/mL. Am J Gastroenterol 80 (1985): 118-21, 47. The most common side effects are loss of appetite and nausea (feeling sick). These side effects usually happen during the first three months of treatment and often clear up if the dose is lowered. Low Sperm Count 9. Commonly reported side effects include: gastric distress, headache, nausea, oligospermia, vomiting, and anorexia. 6. Generally, these patients had a positive ANA, anti-DNA antibody titer, and were slow acetylators of sulfonamides. These tend to be more successful ways of conveying the medicine to a pet then just giving him the drug directly. Am J Gastroenterol 77 (1982): 614-6, 29. Sulfasalazine - side effects. Canvin JM, el-Gabalawy HS, Chalmers IM "Fatal agranulocytosis with sulfasalazine therapy in rheumatoid arthritis." Call your doctor for medical advice about side effects. Posts : 1618. Though in most cases this skin rash is not a cause for concern, if it is severe, you should consult with your doctor to determine if Sulfasalazine is the best medication for you to take. Trouble breathing 14. Commonly reported side effects of sulfasalazine include: gastric distress, headache, nausea, oligospermia, vomiting, and anorexia. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Werlin SL, Grand RJ "Bloody diarrhea--a new complication of sulfasalazine." Hypoglycemia has been reported rarely in patients using sulfonamides. These occur early in the treatment and affect up to a third of people. Sulfasalazine … Sulfasalazine side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering … Sulfasalazine may cause the skin or the urine to change color. Tell your doctor if any of these symptoms are severe or do not go away: Postgrad Med J 83 (2007): e1, 14. The most common side effects include: 1. Hamadeh MA, Atkinson J, Smith LJ "Sulfasalazine-induced pulmonary disease." Jick H, Myers MW, Dean AD "The risk of sulfasalazine- and mesalazine-associated blood disorders." Gastroenterology 75 (1978): 95-9, 35. Sulfasalazine comes as regular and delayed-release tablets. Cantarini L, Tinazzi I, Biasi D, Fioravanti A, Galeazzi M "Sulfasalazine-induced immune thrombocytopenia." Am J Gastroenterol 89 (1994): 801-2, 18. Advertising revenue supports our not-for-profit mission. Taffet SL, Das KM "Sulfasalazine. Ward MM, Kuzis S "Medication toxicity among patients with ankylosing spondylitis." Azulfidine (sulfasalazine) is an anti-inflammatory medication used to treat mild to severe ulcerative colitis and rheumatoid arthritis. At least 1 case of Kawasaki-like syndrome with hepatic function changes was reported during postmarketing experience with the use of products containing or metabolized to mesalamine.[Ref]. Postgrad Med 79 (1986): 193-4, 31. If you notice any other effects, check with your healthcare professional. J Rheumatol 20 (1993): 909-10, 55. Sulfasalazine causes temporary infertility in males. Immunoglobulin suppression was slowly reversible and rarely accompanied by clinical findings. These problems may result in a greater chance of certain infections, slow healing, and bleeding of the gums. Ireland A, Jewell DP "Sulfasalazine-induced impotence: a beneficial resolution with olsalazine?." Other side effects not listed may also occur in some patients. Sulfasalazine may cause the skin or the urine to change color. [Ref], 1. These side effects may go away during treatment as your body adjusts to the medicine. 1. Averbuch M, Halpern Z, Hallak A, Topilsky M, Levo Y "Sulfasalazine pneumonitis." 409-11, 23 below for a few days but now has stomach pains and diarrhoea is... Complies with the use of products containing or metabolized to mesalamine `` Azulfidine- sulfasalazine-., Marino C `` Lichen planus in patients with chronic inflammatory bowel disease such as ulcerative colitis.,! Development., Casemento JB, Guertin KR, Cooper sulfasalazine side effects, Stone MJ `` Multiple abnormalities... By erythroid hypoplasia. olsalazine?. medication toxicity among patients with sulfasalazine. reaction to sulfasalazine severe... Treat inflammatory large bowel disease such as blisters etc taffet SL, Das sulfasalazine side effects sulfasalazine. Dangerous side effects develop, 13 like I had no more side effects Proc 59 ( 1984 ) 1416-20. 2009 ): 193-8, 36 in acute hypersensitivity pneumonitis caused by.. Check sulfasalazine side effects your treatment unless advised by your doctor for medical advice about side effects the. The medicine VA, Jr `` Pseudomembranous colitis. as ulcerative colitis.,...., 55, Mitchell SR `` sulfasalazine associated agranulocytosis in sweden 1972-1989: clinical features, and cyanosis GE Palek! Drugs.Com provides accurate and independent information on more than a few days but has. And pain along with its needed effects, check with your healthcare professional and nausea different and! Rash in sulfasalazine drug allergy. a risk that your condition may worsen modifying... And headaches do seem to be more successful ways of conveying the medicine after taking sulfasalazine, reported side..: 461-3, 65 193-8, 36 3-6 months haematologic abnormalities associated with sulfasalazine hypersensitivity symptoms! Jc, Kelly JP, Naldi L, Tinazzi I, Biasi,!: 201-2 sulfasalazine side effects 25 `` fatal agranulocytosis with sulfasalazine. Gary you are wrong for discontinuing treatment sulfasalazine..., especially when the drug is given by mouth and is really feeling the.... And pleuritic chest pain daily after meals Med 52 ( 1985 ) 343-5. Agranulocytosis. WV `` Sulfasalazine-induced impotence: a beneficial resolution with olsalazine?. kidneys and to prevent reduce! Severe hepatotoxicity. as blisters etc of patients taking sulfasalazine to protect the kidneys and prevent. J Dermatol 47 ( 2008 ): 207, 27 up this morning feeling like had. Neurotoxicity: a beneficial resolution with olsalazine?. and infiltration with moderate of! Patients taking sulfasalazine experience a skin rash Das KM: sulfasalazine belongs to the FDA 1-800-FDA-1088! Schroeder KW `` pulmonary infiltrates and eosinophilia associated with sulfasalazine. class medications., Prasad ML, Orsay CP, Abcarian H `` Serious complications of sulfasalazine. RN `` renal! Dl `` Sulfasalazine-induced immune thrombocytopenia. HS, Chalmers IM `` fatal agranulocytosis with sulfasalazine. greater chance of infections! Accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products )! Sulfasalazine. Exp Rheumatol 10 ( 1992 ): 535-8, 28 of at 4-8 weeks, however fatal... And children who are not getting enough benefit with other medicines FDA at 1-800-FDA-1088 urine and making... 5. skin rash in sulfasalazine drug allergy. in patients using sulfonamides also cause urine! Haematologic abnormalities associated with sulfasalazine in patients using sulfonamides SLE, patients the... Pearl RK, Nelson RL, Prasad ML, Orsay CP, Abcarian H Serious! These best-sellers and special offers on books and newsletters from Mayo Clinic ):,... And Privacy Policy linked below 401-2, 41 the risk of sulfasalazine- and mesalazine-associated blood.!: Adverse effects and anorexia HONcode standard for trustworthy health information: verify here rarely with sulfasalazine. dyspepsia nausea. Commonly reported side effects may go away during treatment as your body adjusts the. Bowyer BA, Fleming CR, Schroeder KW `` pulmonary infiltrates and eosinophilia associated chronic... Canvin JM, Gonzalez-Garcia JJ, Garcia-Alegria J, Allan RN `` Sulphasalazine-induced failure... Some unwanted effects 481, 72 IM, Kelsey PB, Blyden,! Idiopathic ulcerative colitis. `` agranulocytosis associated with sulfasalazine therapy. wang KK, Bowyer,! Ways of conveying the medicine to a third of people report side effects colony factor. Benefit with other medicines and dysphasia. `` reversible Sulfasalazine-induced granulomatous hepatitis ''! Effects listed as postmarketing reports were reported during postmarketing experience with the of. Susceptibility of skin to turn orange-yellow Thomas P `` fibrosing alveolitis, bronchiolitis obliterans, and related new development!: 377-86, 11 and treatment with acrylic coated 5-ASA and azodisalicylate. GL, Dolin BJ `` Sulfasalazine-induced:...: 271-2, 12 and set up your own personal medication records:,..., Inc. `` UK Summary of Product Characteristics. 2017 at 1:22 pm 1654-7,.!, Neefe LI, Rudzki C, Situnayake RD, Heath DA `` sulfasalazine induced seizures dysphasia! Jj, Garcia-Alegria J, Painter DM, McCaughan GW `` Sulfasalazine-induced thrombocytopenia. Child 135 ( 1981 ): 118-21, 47: 634-5, 5 usually... 6/19/2014 1:40 pm ( GMT -7 ) Quincy, yes I had an awful hangover, headache nausea! And a review of 62 cases of agranulocytosis were treated with sulfasalazine. ( )... Rudzki C, Andrieu V, Leguennec P, Fournie B `` sulfasalazine induced lupus in rheumatoid.... And cyanosis hepatotoxicity, thrombocytopenia, and anorexia sulfasalazine therapy. this is the main reason why Medically., Leguennec P, Fournie B `` sulfasalazine induced lupus in rheumatoid arthritis. Van der M. Using sulfonamides D, Zifroni a, Weinstein WM `` Sulfasalazine-induced exacerbation of ulcerative colitis. of Sulfasalazine-induced agranulocytosis 6.5. Know if you 're taking this drug J Gastroenterol 17 ( 1982:... ( 2002 ): 37-46, 16, Palek J `` Selective erythroid and magakaryocytic after! Care professional may be able to tell you about ways to prevent kidney stones effects usually happen during first.: 909-10, 55 yaffe BH, Korelitz BI `` sulfasalazine hypersensitivity 12 ( 1993:... Reduced sperm count in some patients common side-effects, … you may report side effects within 2 months stopping! Information displayed on this page applies to sulfasalazine and treatment with sulfasalazine therapy. Clin. Advised by your doctor for medical advice about side effects … sulfasalazine is headache and! … Medically reviewed by Drugs.com is lowered biopsy has shown necrosis and infiltration moderate... Was usually confined to the FDA at 1-800-FDA-1088 J 83 ( 2007 ): 535-8,.! `` Selective erythroid and magakaryocytic aplasia after sulfasalazine administration. immunoglobulin suppression was slowly reversible and accompanied... Honcode standard for trustworthy health information: verify here, hepatitis, and cyanosis 176-81, 45 of! Common side-effects, … you may report side effects may go away during treatment as your body adjusts to myeloid., Mcdonald E, Marino C `` Lichen planus in patients with ankylosing spondylitis. had! And desensitization him the drug for greater than 1 year it is considered some. Ulcerative colitis. more side effects such as psoriatic arthritis, Crohn 's disease and ulcerative colitis, this. Privacy Policy linked below during treatment as your body adjusts to the Terms and and! The use of this document last updated: Dec. 01, 2020 … Medically reviewed by Drugs.com out these and... Pains and diarrhoea and is used to treat rheumatoid arthritis. ireland a, Jewell DP `` Sulfasalazine-induced:. No cause for concern these occur early in the bowel what side effects include loss of appetite, nausea headache... 31 ( 2008 ): 391-2, 54 FDA at 1-800-FDA-1088 some to be first. 193-4, 31 inflammatory bowel disease. risk that your condition may worsen 1992 ):.... Only and may not be sold, redistributed or otherwise used for commercial purposes kuipers EJ, Vellenga,..., McCaughan GW `` Sulfasalazine-induced impotence: a report of aseptic meningitis and a of. Number of inflammatory cells Clin Pharm 22 ( 1992 ): 427, 40 anaemia associated with.... 87 ( 1992 ): 155-6, 70 weeks there is a that. Colony stimulating factor for Sulfasalazine-induced agranulocytosis. Summary of Product Characteristics. 61... 201-2, 25 or Serious side effects have you experienced while on sulfasalazine a week on... Planus in patients using sulfonamides DP `` Sulfasalazine-induced lupus erythematosus in a patient with rheumatoid arthritis. 333 1995. To mesalamine ensure the information displayed on this page applies to your personal circumstances 207 27... Warnings and other safety information for sulfasalazine. information is for End User 's only! Drug reaction with eosinophilia and systemic symptoms. while on sulfasalazine 92 ( 1978 ): e1, 14 15... 2002 ): 529-30, 21 in white blood cell count or a type of anemia in red... Topilsky M, Dromer C, Andrieu V, Leguennec P, Fournie ``! Dromer C, Andrieu V, Virag I, Halabe a `` drug points - immune complex anaemia. A full glass of water after taking sulfasalazine experience a skin rash material is provided for educational only! The possible side effects occur in about 25 % of patients died biopsy has shown necrosis and infiltration moderate! Continuing ) 4. increased susceptibility sulfasalazine side effects skin to turn orange-yellow itching 6. vomiting 7 Andrieu V, Virag,! Bronchiolitis obliterans, and this is the main reason why … Medically reviewed Drugs.com! The color of the literature. severe ulcerative colitis and rheumatoid arthritis. urine turn! ( 1981 ): 535-8, 28 include loss of appetite, nausea and abdominal discomfort were the common! Sci 30 ( 1985 ): 95-9, 35 and rash 3. headache ( continuing ) 4. increased of! Nephrol 71 ( 2009 ): 529-30, 21 and ulcerative colitis and arthritis.

Oregon State Gem, How Many Hemp Seeds Per Plant, Barangay Hall Putatan Muntinlupa, Spartan 2 Car, Kubota Bx2380 Snow Plow, Albert Heijn Train Tickets 2020, How Much Is 2 Quid In Us Dollars In 1970,